Oral Suspension for Cats less than 6 months of age or in debilitated aged animals may involve additional risk. If use in such animals cannot be avoided, a reduced dosage and careful clinical management may be required. This can result in symptoms such as feeling full during or just after eating bloating, belching, nausea, heartburn and stomach ache. Corona, CA 92880 USA. Domperidone 10mg Tablets are white coloured, round, biconvex tablets. The active ingredient is domperidone maleate. Each tablet also contains several inactive ingredients. These include lactose monohydrate, maize starch, microcrystalline cellulose, povidone, magnesium stearate, colloidal anhydrous silica and sodium laurilsulfate.
The Cat Owner's Guide to Parasites. ELANCO CANADA LIMITED successor to Novartis Animal Health Canada Inc. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert. Use the lowest effective dose for the shortest duration of treatment consistent with the individual clinical response. Medication side effects include nausea, vomiting, stomach upset, weakness, dizziness, seizures, and more.
Elanco, Fortekor, Flavor Tabs and the diagonal bar are trademarks owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates. Benazeprilat acts by inhibiting angiotensin converting enzyme ACE. This enzyme is part of the renin-angiotensin cascade system and converts inactive Angiotensin I into biologically-active Angiotensin II, the hormone controlling vasoconstriction and release of aldosterone. Thus, ACE inhibitors prevent constriction of the blood vessels, thereby facilitating blood flow and reducing hypertension. Distributed by ELANCO, Division Eli Lilly Canada Inc. Typical adverse reactions of NSAIDs, such as loss of appetite, vomiting, diarrhea, apathy and renal failure have occasionally been reported. These adverse effects are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal.
If you miss a dose of codeine sulfate and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Drug hypersensitivity reactions 6. Ophthalmic diseases. ACTH production and in turn adrenocortical activity.
It should be noted that suspected adverse drug reactions listed here reflect reporting and not causality. The categories of adverse reactions are listed in decreasing order of frequency by body system. In rare cases, death has been associated with some of these adverse reactions. Codeine sulfate is to be used only by the patient for whom it is prescribed. Do not share it with other people. Safety Studies: Studies on cats receiving meloxicam have demonstrated much higher sensitivity to NSAIDs than dogs. HPA may be helpful in understanding this rationale. Myelodysplastic syndromes are diseases that affect the bone marrow and blood, causing anemia and tiredness. INDICATIONS 1. Endocrine disorders. If codeine sulfate is no longer needed, check with your pharmacist for ways to properly dispose of codeine sulfate. Do not throw it in the trash. Do not use your Domperidone 10mg Tablets after the expiry date printed on the package. If you have any tablets that are out of date, please return them to your pharmacist for disposal. References available upon request. This leaflet was last revised in April 2012. Warning: Keep out of reach of children. Oral Suspension for Cats was the change from baseline of the Clinical Sum Score CSS calculated by adding the single scores of posture, lameness and pain on manipulation. No significant differences between groups were observed for any of the clinical, biochemical or pathological outcomes evaluated. The usual dose for the treatment is 1 to 2 tablets taken 3 to 4 times a day before meals. Do not take more than 8 tablets 80mg in 24 hours. NSAID of the oxicam group. It acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory and analgesic effects. These tablets contain lactose monohydrate. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Use within 6 months after first opening. This reaction may be more likely to occur in children. This medicine has been prescribed for you personally and you should not pass it on to others. It may harm them, even if their symptoms are the same as yours. Pharmacodynamic Properties: FORTEKOR contains benazepril hydrochloride, a prodrug hydrolysed in vivo to benazeprilat which inhibits angiotensin converting enzyme ACE thus preventing the conversion of inactive angiotensin I into active angiotensin II. FORTEKOR reduces all effects mediated by angiotensin II, including vasoconstriction of both arteries and veins and retention of sodium and water by the kidney. FORTEKOR causes long-lasting inhibition of plasma ACE in dogs and cats, with significant inhibition persisting for 24 hours after a single dose. FORTEKOR reduces the pressure and volume load on the heart in dogs with heart failure, and leads to improvements in the quality of life and clinical signs, notably coughing. FORTEKOR also produces a significant reduction in the frequency of mortality as compared to conventional therapy, consistent with an extension in life span. In cats with chronic renal insufficiency, FORTEKOR reduces the protein loss in urine and lowers the systemic and intraglomerular blood pressure. Your doctor may advise you to take your medicine in a different way, so you should always follow your doctor s advice about how and when to take your medicine and always read the label. If you feel that the effect of Domperidone 10mg Tablets is too strong or too weak, talk to your doctor or pharmacist. Histopathology demonstrated slight to minimal papillary necrosis in the kidneys and mucosal erosion in the 3X and 5X groups. No treatment related changes were noted in the 1X group.
The safety of FORTEKOR has not been tested in breeding dogs. The investigators conducted a clinical examination comprising general examination and specific examination of the musculoskeletal system at inclusion, on day 0 and at the end of treatment day 5. These examinations included feed intake, general behaviour, posture, lameness and pain on manipulation assessments and rectal temperature measurement. In addition, at the end of the treatment, the investigator evaluated the overall efficacy and palatability of the treatment. Diseases of the limbs, especially soft tissue injuries contusions and joint disorders sprains and luxations of less than 2 weeks duration were the most frequently diagnosed. Polycystic kidney disease can cause abdominal pain, headaches, and pain in the sides and back. Keep this leaflet. You may need to read it again. Symptoms may include blue lips or nails; cold and clammy skin; coma; confusion; hallucinations; limp muscles; loss of consciousness; mood or mental changes; seizures; severe dizziness or drowsiness; slow heartbeat; slow or shallow breathing; sluggishness; small or large pupils. HPA activity on the off-steroid day. VZIG may be indicated. All corticosteroids increase excretion. This may not be a complete list of all interactions that may occur. Ask your health care provider if codeine sulfate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. One cat in each group was clinically depressed on the last day of treatment. Duodenal ulceration and secondary peritonitis were observed at necropsy. Ask your health care provider any questions you may have about how to use codeine sulfate. Merck Veterinary Manual: "Sporotrichosis. If you take more tablets than you should, tell your doctor immediately or go to the nearest hospital. Pharmacokinetic Properties: Benazepril is rapidly but incompletely absorbed from the gastrointestinal tract following oral administration. Absorbed benazepril is partially hydrolyzed by hepatic enzymes to the active substance, benazeprilat; unchanged benazepril and hydrophilic metabolites account for the remainder. Peak plasma benazeprilat concentrations are attained within about two hours both in fasting and fed situations. Benazepril and benazeprilat are bound to plasma proteins, and in tissues are found mainly in the liver and kidney. The major part of benazeprilat is rapidly eliminated, although there is in addition a slow terminal elimination phase. Benazeprilat is excreted approximately equally via both biliary and urinary routes in dogs and primarily via the biliary route in cats. Repeated administration of FORTEKOR leads to slight accumulation of benazeprilat in plasma; steady state is attained within four days. Because of its biliary excretion route, there is little risk of bioaccumulation of benazeprilat in dogs with impaired renal function. For this reason, no dose adjustment of FORTEKOR is necessary in cases of renal insufficiency.
Cats with Dry, Flaky Skin. Cat Care -- Ear Mites. Codeine sulfate may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation. See USP controlled room temperature. You may be given active charcoal, which can prevent the absorption of domperidone, if taken soon after having taken the overdose. Symptoms of overdose are drowsiness, disorientation, irregular eye movements and strange movements of the body, especially in children. Fortekor 5 mg and 20 mg - palatable beige to light brown tablets which are scored on both sides, and contain either 5 mg benazepril hydrochloride Fortekor 5 mg or 20 mg benazepril hydrochloride Fortekor 20 mg.
If gastrointestinal or other adverse reactions occur, treatment should be discontinued immediately and the advice of a veterinarian sought see Adverse Reactions. The name of your medicine is Domperidone 10mg Tablets. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Severe 5. Allergic states. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. Store codeine sulfate at room temperature, between 59 and 86 degrees F 15 and 30 degrees C. Store away from heat, moisture, and light. Do not store in the bathroom. Keep codeine sulfate out of the reach of children and away from pets. Each tablet contains 10mg domperidone as domperidone maleate. When used for long periods of time or at high doses, codeine sulfate may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if codeine sulfate stops working well. Do not take more than prescribed. Please read this leaflet carefully before you start to take your medicine. As an aid in the management of chronic renal insufficiency associated with proteinuria in cats. Oral Suspension for Cats. FORTEKOR reduced erythrocyte counts in normal cats at high doses, but this effect was not observed at the recommended dose during clinical trials in cats with chronic renal insufficiency. As is routine in cases of chronic renal insufficiency it is recommended to monitor erythrocyte counts during therapy. FORTEKOR is well-tolerated by the target species. Tell your doctor or dentist that you take codeine sulfate before you receive any medical or dental care, emergency care, or surgery. If your complaint shows no improvement after 28 days while taking Domperidone 10mg Tablets, consult your doctor to see if you need to go on taking this medicine. Children weighing less than 35kg 5 stone should not take these tablets.
Systemic: anorexia, lethargy, death. Boehringer Ingelheim Canada Ltd. FORTEKOR can be given with or without food. The duration of treatment is unlimited. When used for long periods of time or at high doses, some people develop a need to continue taking codeine sulfate. This is known as DEPENDENCE or addiction. If you have further questions, please ask your doctor or your pharmacist. DAN 5059 supplied in bottles of 100, and 1000. Codeine sulfate should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed. Hemophilia is a disorder in which the blood lacks certain clotting factors making bleeding difficult to stop. Compendium: Continuing Education for Veterinarians, May 2009. Queen, you and I can always agree to disagree. I love your input and the knowledge you have on so many different topics. Don't let my vent upset you. Oral Suspension were used. If you have any questions about codeine sulfate, please talk with your doctor, pharmacist, or other health care provider. Take your tablets as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as normal. Do not take a double dose to make up for the forgotten dose.
Hepatitis A is an inflammation of the liver. Symptoms include fever, fatigue, yellowing of the skin, and more. Do not take more than the recommended dose or use more often than prescribed without checking with your doctor. This information should not be used to decide whether or not to take codeine sulfate or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about codeine sulfate. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to codeine sulfate. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using codeine sulfate. Of course not things like aluminum foil, rocks, plastics, etc. Check with your pharmacist about how to dispose of unused medicine. The treatment of heart failure in dogs caused by mitral regurgitation or dilated cardiomyopathy, in combination with standard therapy. Renal and urinary: renal disorder, renal failure, urine abnormalities. Repeat dosing in cats at doses higher than currently recommended has been associated with acute renal failure and death. Oral Suspension for Cats in comparison to the positive control was shown and thus proved efficacy. Merck Veterinary Manual: "Eosinophilic Granuloma Complex. Cautions: Particular care should be taken with regard to accuracy of dosing in cats. Do not exceed the stated dose. The incidence of treatment-related gastrointestinal adverse reactions increased with increasing oral dosages and included vomiting, diarrhea and melenic feces. Domperidone should be used at the lowest effective dose in adults and children. The safety of Metacam has not been evaluated in breeding, pregnant or lactating cats. In case of overdosing, symptomatic treatment should be initiated. Increased risks of drug intolerance may occur in patients already debilitated. Avoid use in dehydrated, hypovolemic, or hypotensive cats because of increased risk of renal toxicity. Animals being treated with meloxicam should be monitored for the occurrence of adverse reactions, as susceptibility varies with the individual.
Oral Suspension for Cats meloxicam is a nonsteroidal anti-inflammatory drug NSAID and as with other drugs in this class, adverse reactions may occur in treated animals. The most common adverse reactions reported involve the kidneys and the gastrointestinal tract. Typical symptoms include loss of appetite, depression and vomiting. It is important in these situations to discontinue treatment immediately and contact your veterinarian. In most cases, the adverse reactions are transient and disappear after termination of treatment but in rare instances may be serious especially if treatment is not discontinued. Consult your veterinarian. These tablets have been prescribed for you by a doctor. Take them exactly as he or she has told you. Please read the label carefully. If you suddenly stop taking codeine sulfate, you may experience WITHDRAWAL symptoms, including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping. Some MEDICINES MAY INTERACT with codeine sulfate. The safety of FORTEKOR has not been evaluated in cats with acute renal failure, acute exacerbation of chronic renal failure, hypovolemia, dehydration, or concurrent cardiac or hepatic disease. During the clinical trial, benazepril was administered to cats with elevated ALT levels, without specific adverse events being observed. Renal cell cancer is a type of kidney cancer that can cause bloody urine and persistent pain in the side.
Do not stop taking any medications without consulting your healthcare provider. Transient reversible hypotension may occur in some cases of accidental overdose. Therapy should consist of intravenous infusion of warm isotonic saline solution. If your symptoms do not improve or if they become worse, check with your doctor. Signs of hypotension such as lethargy or ataxia may appear in rare cases. Reduce the dose of the diuretic, if necessary. Do not administer concurrently, other steroidal or nonsteroidal anti-inflammatory drugs NSAIDs aminoglycoside antibiotics or anticoagulant agents. Pre-treatment with other steroidal or nonsteroidal anti-inflammatory drugs NSAIDs may result in additional or increased adverse reactions and accordingly a treatment-free period with such drugs should be observed for at least 24 hours before commencement of treatment depending on the pharmacokinetic properties of the products used previously. All cats should undergo a thorough history and physical examination before the initiation of an NSAID treatment. When possible, appropriate laboratory tests should be conducted to establish hematological and biochemical baseline data before the administration of any NSAID. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; chest pain; confusion; fainting; fast or irregular heartbeat; mental or mood changes; numbness or pain of an arm or leg; seizures; severe drowsiness or dizziness; severe or persistent constipation or stomach pain; shortness of breath; slow or shallow breathing; sudden, severe headache or vomiting; trouble urinating. Many times dogs will eat something the owner never knows about. Unless the dog becomes ill, it usually passes through without a problem. And dogs CAN "tell us when they hurt. No evidence of renal toxicity to FORTEKOR has been observed in dogs during clinical trials. Because of the biliary excretion of benazeprilat, there is little risk of bioaccumulation in dogs with impaired renal function. For this reason, no dose adjustment of FORTEKOR is necessary in cases of renal insufficiency. However, as is routine, in cases of renal insufficiency, it is recommended to monitor plasma urea and creatinine levels. Keep out of reach of children. Blood clotting disorders increase the risk that dangerous blood clots will form in the body. By pushing the plunger in, empty the contents of the syringe onto the food or directly into the mouth. Berger's disease can cause blood in the urine, dark-colored urine, fever, fatigue and more. Oral Suspension for Cats is given in a fasted state, the maximal plasma concentrations are obtained after approximately 3 hours. If the cat is in a fed state at the time of dosing, absorption may be slightly delayed. Approximately 97% of meloxicam is bound to plasma proteins. Meloxicam is predominately found in plasma and is also a major biliary excretion product whereas urine contains only traces of parent compound. Meloxicam is eliminated with a half life of approximately 24 hours. Seventy-nine percent of the recovered dose is eliminated in the faeces and 21% in the urine. All major metabolites have been shown to be pharmacologically inactive.
Adverse events in dogs and cats occur very rarely. The active ingredient is domperidone maleate. Hydronephrosis is a condition of the kidneys and causes aching or pain, urinary symptoms, fever, and nausea. Codeine sulfate may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use codeine sulfate with caution. The syringe fits onto the drop dispenser of the bottle and has a kg-body weight scale which corresponds to the maintenance dose. Although not demonstrated in cats, benazepril may cause hyperkalemia in some human patients with chronic renal failure. Periodic monitoring of serum potassium levels during therapy is therefore recommended. Congenital erythroid hypoplastic anemia 9. Neoplastic diseases. Signs of endocarditis, an infection of the heart, include swelling, rash, sinus congestion, nausea, and more. Use codeine sulfate as directed by your doctor. Check the label on the medicine for exact dosing instructions. All medicines may cause side effects, but many people have no, or minor, side effects.
University College of Veterinary Medicine. Packs of 2 or 4 5 mg blisters. Some patients may have a genetic trait that may cause codeine sulfate to enter their blood faster. This may increase the risk of side effects. Contact your doctor right away if you develop symptoms of overdose, even if you have not taken more than the recommended dose of codeine sulfate. Once control is again established, alternate-day therapy may be reinstituted. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Use within 14 days after the first opening. In man, the combination of ACE inhibitors and NSAIDs can lead to reduced efficacy of the ACE inhibitor or impaired renal function.
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Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. FORTEKOR may increase plasma creatinine concentrations at the start of therapy. This effect is related to the therapeutic effect of the product in reducing blood pressure, and therefore is not necessarily a reason to stop therapy in the absence of other signs. As is routine in cases of chronic renal insufficiency, it is recommended to monitor plasma creatinine during therapy. If taken with other medicines the effect of Domperidone 10mg Tablets or the effects of the other medicine may be altered.
FORTEKOR is well tolerated in the target species. Packaged in plastic blister packs each containing 14 tablets, 2 or 4 blisters to a pack. Kidney infection, caused by bacteria, is marked by sudden chills and fever, pain, nausea and urinary issues.
Do not drink alcohol or use medicines that may cause drowsiness eg, sleep aids, muscle relaxers while you are using codeine sulfate; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. Oral Suspension for Cats measuring syringe provided in the package can be used. For each single parameter of the CSS posture, lameness, and pain on manipulation as well as the secondary parameters feed intake, general behavior, and rectal temperature the differences between the two groups were very small and no statistically significant difference was found between the two treatments.
American Society for the Prevention of Cruelty to Animals ASPCA: "Obsessive Grooming. Constipation; dizziness; drowsiness; lightheadedness; nausea; sweating; tiredness; vomiting. Some medical conditions may interact with codeine sulfate.